What is C60MD?

Discovery & Origin

In 1975, British chemistry professor Harold Kroto and astronomers discovered an unusual carbon species that exists abundantly in interstellar space.

This carbon isotope is found in the outer atmospheres of stars and red giants, forming the third cluster of carbon atoms (C60), besides diamond and graphite.

Crystalline Forms of Carbon

DIAMOND

GRAPHITE

FULLERENE

  • C60, also known as Buckminsterfullerene, was discovered in 1985. Scientists Harold Kroto, Robert Curl, and Richard Smalley won the Nobel Prize in Chemistry in 1996 for their discovery. C60 is the smallest spherical carbon cluster, composed of 60 carbon atoms arranged in a structure resembling a hollow soccer ball, with a diameter of about 1-10 nanometers (nm). Its unique carbon cage structure and conjugated double bonds allow it to combine with free radicals, reducing cellular oxidative stress.

  • Research by Akhtar (2017) found that the antioxidant capacity of water-soluble C60 is 172 times that of vitamin C, earning it the title of "Free Radical Scavenger." Due to the high compatibility of its nano-molecular structure with biological systems, water-soluble C60 easily penetrates cells and mitochondria.

  • Animal experiments by Baati (2012) showed that C60 could double the lifespan of rats by reducing oxidative stress. Due to the physicochemical properties and nano-size of C60 molecules, they can be absorbed sublingually, bypassing the destruction by stomach acid and enzymes, and penetrate deeply into various tissues, significantly improving bioavailability (BA).

C60 MD Technological Background

The technology behind C60 MD products originates from the U.S. company SINAPU LLC CORPORATION, led by Simon Cao and Dr. Butzloff. Their unique technology derives from Richard Smalley, the father of carbon nanotubes, and combines quantum physics and nanotechnology to develop water-soluble C60 (fullerenol), greatly enhancing oral bioavailability (BA). This technology gives C60 nano-drug delivery capabilities, allowing it to penetrate the blood-brain barrier (BBB) and treat brain-related diseases such as Parkinson's, Alzheimer's, and dementia. These significant breakthroughs make water-soluble C60 highly promising for future preventive medicine and health applications.

Unique Properties & Advantages

Characteristics and Benefits of Fullerenes (C60)

  • Fullerenes have unique photochemical, electrochemical, and physical properties, making them widely applicable in nanomedicine.

  • Their conjugated double bonds and unique carbon cage structure,combined with their ability to easily undergo derivatization, make thempotential therapeutic agents.

  • They are known as free radical scavengers, with antioxidant effectshundreds of times greater than traditional antioxidants.

  • Complexes formed by combining fullerenes with hyaluronic acid andnatural antioxidants can stabilize molecular structures, promoting humanabsorption and increasing bioavailability.

  • The combination of fullerene nanotechnology and medicine could lead tothe development of nano-vaccines or drug carriers, creating milestones infuture disease treatment.

    (Petrovic et. al, 2015 J. Nanomaterials)

Physicochemical Properties of Fullerenes (C60)

Molecular Size and Cell Permeability of Fullerenes (C60)

The C60 molecule is composed of 60 carbon atoms, forming a structure similar to a hollow soccer ball with a diameter of approximately 1–10 nanometers (nm). This unique carbon cage structure with conjugated double bonds enables C60 to bind with free radicals, effectively reducing cellular oxidative stress. The nanoscale, water-soluble structure of C60 is highly compatible with biological systems, allowing it to easily penetrate cells and mitochondria. With 172 times the antioxidant capacity of vitamin C, it is often called a “free radical scavenger.” Thanks to its physical and chemical properties and nanoscale size, C60 can be absorbed sublingually, bypassing stomach acid and digestive enzymes, allowing it to deeply permeate various cell tissues and significantly increase bioavailability (BA).

 Sinapu LLC Corporation

Simon Cao

Chairman & CEO Ph.D

Pete Butzloff

Chief Scientist Ph,D

Sean Chen

Founder & COO  J.D./P.E.

Technological Background

The technology behind C60 MD products originates from the U.S. company SINAPU LLC CORPORATION, led by Simon Cao and Dr. Butzloff. Their unique technology derives from Richard Smalley, the father of carbon nanotubes, and combines quantum physics and nanotechnology to develop water-soluble C60 (fullerenol), greatly enhancing oral bioavailability (BA). This technology gives C60 nano-drug delivery capabilities, allowing it to penetrate the blood-brain barrier (BBB) and treat brain-related diseases such as Parkinson's, Alzheimer's, and dementia. These significant breakthroughs make water-soluble C60 highly promising for future preventive medicine and health applications.